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NEWS

UHS faculty member honoured

The World Organization of Family Doctors (WONCA) has added Dr Hina Javed of the University of Health Sciences (UHS) to its list of “Featured Doctor.” Dr Hina Javed is the second family physician from Pakistan to receive this honour.

Dr Hina Javed is currently serving as an assistant professor at the UHS Family Medicine department. The World Organization of Family Physicians has more than 500,000 family doctors from 131 countries as its members. Each month, the organization selects two family doctors from around the world for the honour based on outstanding performance. This month, Dr Hina Javed from Pakistan and Dr Gorcia Guterres Gomez from Spain have been selected.

Dr Hina Javed was given this award for raising public awareness in the field of primary care. She has done significant work in the field of antibiotics stewardship and injection safety. She also trained young doctors for telemedicine services during the coronavirus pandemic. UHS Vice-Chancellor Prof. Javed Akram has congratulated Dr Hina Javed on this achievement.

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NEWS

UVAS syndicate approves Rs.2.968 billion budget

The Syndicate of the University of Veterinary and Animal Science Lahore has approved Rs.2.968 billion budget for the financial year 2021-22, focusing on innovation, applied research, development, improving facilities for quality of education, services and transfer of technology.

Chairing the 66th Syndicate meeting, Vice-Chancellor Prof Dr Nasim Ahmad said that the focus is on applied research and development projects for further improving the quality of education, research and services at the university. The value of the ongoing 88 research projects is Rs.1.082 billion.

Prof Nasim Ahmad told the meeting that Rs.713.299 million has been allocated for development projects. Of the total development allocation, Rs 428.299 million will be spent on ongoing projects while Rs.285 million on new projects to be initiated in the financial year 2021-22. The Vice-Chancellor said that Rs.200 million have been allocated for a new project “Establishment of UVAS Sub-Campus at Chichawatni”, Rs.50 million for the new project “Strengthening of Capacity Building Facilities at Para Veterinary Institute, Karor Lal Eason Layyah”, Rs.78.3 million for new project establishment of girls and boys hostels in university and Rs.35 million also allocated for new Project “Capacity Building of Dairy Farmers and Industry Stakeholders on Milk Value Chain”.

Among the ongoing projects, the Vice-Chancellor said that Rs.350 million have been allocated for “Enhancement of Research Facilities at UVAS Ravi Campus Pattoki”, Rs.78.299 million for “Provision of Urgently Needed Male and Female Hostel Facilities at University of Veterinary & Animal Sciences”.

Earlier, presenting the budget before the Syndicate, Treasurer Mr Muhammad Umar said that the university expects non-development income of Rs.2.064 billion from different sources during the year 2021-22 while non-development expenditure is expected at Rs.2.254 billion, so there is a deficit of Rs.190.357 million.

The Vice-Chancellor said that Rs.1.133 billion are expected to be generated by the university from its own sources. About the deficit, he said the university will try to meet the budget deficit by generating more income from its own resources, by increasing its research-based products and diagnostic and clinical services for stakeholders. Special austerity measures will also be adopted to limit the recurring expenditure within available funds, he added.

Earlier, the Vice-Chancellor briefed the syndicate members on various academic, research training programmes, virtual trainings, online seminars/webinars, UVAS in collaboration with Society for Prevention of Cruelty to Animals (SPCA) conducted hands on training of “Dog Castration Surgery” for the control of stray dog population to curb rabies, free Covid-19 vaccination desk set up at UVAS for staff, memorandum of understanding (MoU) for the promotion of education & research with different institutions and livestock, poultry and dairy industries for the internships of students to learn about practical experience/innovative knowledge and university development projects, etc. VC also mentioned UVAS BSL-3 providing COVID-19 free testing services and has tested more then 280,000 throughout pandemic. Prof Dr Nasim Ahmad also lauded the role of budget staff of the UVAS Treasurer’s Office for preparing the budget.

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NEWS

Noam Chomsky Speaks at Habib University

Chomsky to speak at the Habib University today
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NEWS

Punjab Govt. to Employ Tech Services to Monitor Private Schools

Punjab Government draws on tech to monitor private schools   

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FEATURES

Pakistan Must Invest More in Early Childhood Education Programs

Early Childhood Education (ECE) is most often believed to be restricted to acquiring basic skills. However, it plays a crucial role in the child’s intellectual development and growth. ECE largely incorporates learning through play that helps children get acquainted with new environments and experiences. Apart from developing cognitive and social skills, it contributes to fostering healthy communication with their parents, teachers and peers.

For the uninitiated, early childhood is defined by UNESCO as the period from birth to the age of eight and is considered a time when brain development is at its peak. Early Childhood Education aims at the “holistic development of a child’s social, emotional, cognitive and physical needs”, as per UNESCO’s definition, and is, therefore, considered an important time in children’s lives when they first learn to interact with others as their secondary socialization begins.

Early Childhood Education, however, refers to educational programs, strategies and activities aimed to affect the developmental changes in children by the time they reach elementary school.

Even though early childhood education is highly beneficial for the growing mind, over 175 million children globally are not receiving any form of pre-primary education as per to the UN reports. Pakistan apparently has a better pre-primary enrollment ratio compared to its neighbors in the east including India and Bangladesh. However, the country falls short when it comes to keeping students in the system. In fact, Pakistan happens to have the second-highest number of out-of-school children (OOSC) with an estimated 22.8 million children aged 5-16 not attending school altogether.

Early childhood education has historically been a neglected area within the Pakistani education framework. The deficient public provision has over the years been supplemented with private schools mostly located in urban areas, many of which are not accessible for low-income families.

“Disparities based on gender, socio-economic status, and geography”, stated by UNICEF Pakistan’s website, pose as a major challenge in the provision of education in Pakistan.

According to Human Rights Watch, 11% more girls compared to boys are out of school in Pakistan. The disparity based on gender has several reasons including social norms and a lacking educational infrastructure mostly in the interior regions of all the provinces. UNICEF Pakistan’s data for OOSC clearly states that 58% of girls from the poorest regions in Sindh and a staggering 78% of girls from Balochistan’s similar socio-geographic makeup are not attending school.

The neglect towards ECE in Pakistan can be seen as an important factor for the soaring figures of out-of-school children. ECE programs could help reduce the risk of children dropping out of school early as it instills education-positive behavior in children from a younger age. It would not be unjust to state that ECE is a rather significant investment that a country can make to promote human resource development. Studies have shown that there are long-term positive effects of ECE on employment, labor force participation and earnings. According to an estimate, investing in quality ECE can yield significant returns anywhere from 2-13 dollars per person.

Restrictive education budgets

Unfortunately, Pakistan has had a history of dwindling investment in the education sector with the spending (% of GDP) dropping to the one of the lowest at 2.3% in the fiscal year 2019-20. In 2019, the country ranked 152 out of 189 countries in the United Nations Development Program’s (UNDP) Human Development Index (HDI) ranking. The reason for Pakistan’s poor performance attributes to its failure at demonstrating any progress in key educational indicators, such as literacy rate, gross enrolment ratio, and expenditure on education, as compared to the adjoining regional territories as detailed in a report titled Education Budget of Pakistan by Pakistan Girls Alliance for Education.

The report further states that, “compared to international benchmarks, the allocated budget for education is lowest as of the agreed targets of 15-20% of the total budget and 4% of the GDP.”

When it comes to early childhood education and primary education affairs, the government has reserved a total of Rs. 2.931 billion for 2020-21, a slight increase from Rs. 2.83 billion for 2019-20.

Since the early 1990s, Pakistan’s education expenditure has experienced many ups and downs. The country experienced a steady increase from 7.89% in 1993 to 11.75% in 1997 before dropping to about 8% in the year 2000. The country’s education budget saw a definite boom with it reaching a good 15.45% in 2007. Over the years each successive government tried to sustain the budget with most years seeing it above 10%. In 2017, the percentage of spending was closer to 15% at 14.54%. However, in the same year countries such as Bhutan, Uzbekistan and Ghana where spending 24.04%, 23.03%, 20.10%, respectively.

Lack of funding is perhaps the only reason why Pakistan has not been able to develop a proper ECE system. It was only in the 1970s that the concept of pre-primary education was introduced with ‘katchi’ classes. However, it took almost 30 years for these initial school-years to become a part of the national education policy.

The current government has started investing in the pre-primary education affairs in the country.

Benefitting from a perspective change  

Countries across the world have recognized and realized the long-term benefits of ECE for children, which include language development, improved health behaviors, and high economic returns. Several academic studies have endorsed the benefits of ECE.

A study of more than 60,000 children published by Boston College, Lynch School of Education found that by the age of three, ” language improvement of low-income children attending early education and care has led to a significant narrowing of the gaps in the language skills between low-income and high-income children”

Another study published by the Columbia University’s Mailman School of Public Health in 2011 established that intensive education intervention starting in infancy leads to better health behaviors in young adults. One of the benefits included lower depression rates in teenagers.

An extensive study also found that people who participated in ECE were less likely to be on welfare as adults compared to those who had not received any early childhood education.

However, the overall effectiveness of an early childhood program remains dependent upon several factors including quality staff, an appropriate environment, proper grouping practices, consistent scheduling, and parental involvement, according to research.

Pakistan, with its few public schools, limited resources and the issue of ghost-teachers benefitting from the government payroll is a telltale sign that the country has a long road ahead to making education available to all children out-of-school.

An international study led by Sharon Lynn Kagan, an early childhood education professor, compiled in “The Early Advantage 1: Early Childhood Systems That Lead by Example,” examined the top-performing education systems in the world. Several countries have been studying to outline how they have successfully structured early learning systems. Among these include Singapore where it was found that consolidating Early Childhood Education and Care (ECEC) into one autonomous agency increased the focus on ECEC. In South Korea, however, the study established that ECEC programs were incentivized to encourage its population to procreate as “a looming population cliff derived from persistent low fertility rates.”

England, Australia, and Hong Kong are the three other systems studied in depth by Kagan and her fellow researchers, which offer a lot of insight to other countries with lagging ECEC programs, including Pakistan.

The strategies for developing ECEC programs may vary depending on each country’s specific needs, but there is a constant – they all view ECE as an investment with major returns.

The way ahead for Pakistan

Undoubtedly efforts are being made by organizations to make education accessible to children across Pakistan with a focus on providing learning and livelihood opportunities for youths and adults, and rehabilitating vulnerable groups including those forced into child labor. However, a massive improvement in investment and funding by the government is the only way forward.

It is absolutely crucial that Policymakers, teachers, parents and other concerned parties are sensitized to the importance and significance of ECE.

Even more important is making a clear distinction between pre-primary and primary education. Preschools are as important to a child’s education process as any other level of schooling. “Adequate funds should be allocated, released and optimally utilized for the implementation of ECE programs, plans and projects at all levels: i.e. national, provincial and district,” as stated in a paper titled Early Childhood Education in Pakistan: an international slogan waiting for national attention, 2011.

Pakistan needs more public schools with better facilities and improved infrastructure. The most common reason cited by parents for not sending their children to school, especially in the more remote regions, is the distance a child may have to travel to get to school.

Another important factor is poverty. Parents from the lower strata of society often deal with the question of feeding children or educating them. Pakistan needs more public schools with better facilities and improved infrastructure, so that education becomes more accessible.

Furthermore, corruption is so deeply embedded within the education system that even with the current government’s anti-corruption rhetoric and focus on organizational accountability, improvements are far fewer if any.

There are daunting problems that need to be resolved in order to strengthen the education system as a whole. Nonetheless, early childhood education for all children irrespective of gender and socio-economic status must now become a focal discussion because not only can it enhance children’s interest in learning, but can improve their cognitive health, as proven through research.

The government must make an organized effort to retain and enroll children in schools across the provinces and must increase its educational expenditure at the earliest, only then can there hope for Pakistan truly moving forward towards improvements in the provision of Early Childhood Education. It is high time to make an investment in the future of our children and by extension that of the country.

Related: Early Childhood Education Teachers Baton-Charged by Sindh Police
Categories
NEWS

New App for Special Needs Students

At a launch attended by Minister for Human Rights, Dr Shireen Mazari, on Thursday, Oct. 23rd, Pakistan introduced a first-of-its-kind smartphone app geared toward helping parents of Pakistani students with special needs. This application marks the beginning of the introduction of much-needed tech-based improvements in the special needs education sector.

One of the primary objectives of the app is to aid parents of special needs students in the selection of the best-suited education center for their children. The app will help them narrow down their options based on information such as facilities offered by these schools, admission processes as well as their geographic location. The app will also enable parents to apply for admissions at these institutions – falling under the ambit of the Directorate General of Special Education (DGSE) – from home, having shifted the process to an online platform.

While attending the launch as the Guest of Honor, Minister for Human Rights, Dr Shireen Mazari, lauded the efforts of the DGSE as well the National Information Technology Board (NITB). Both institutions had worked in tandem for the development of the app, which the Minister claimed would help an estimated 30,000 out-of-school students be included in the education stream.

Related: Punjab Government Launches “Taleem Ghar” App for Remote Learning
Categories
FEATURES HEALTH AND WELLBEING

Modern-Day Mental Health Issues of Students

Students’ mental health and their well-being are more important than ever before

by Intsab Sahi

It would be a safe bet to say that students in the year 2020 have a lot more to stress about than just going to class. Due to the global pandemic, campuses were forced to shutter up for the better part of this year leaving students little time to adjust to the idea of digital classrooms. Never before have students been obligated to adapt to such sweeping changes to their learning methods.

Prior to the worldwide onset of coronavirus, students across the spectrum had healthy outlets to channel their stresses on campus. From extracurricular activities to group study sessions, there were always plenty of activities happening in schools and university campuses to buffer the classroom stress.

Now, more than ever, the presence of a mental health professional for students is needed in schools and universities alike. Even though attitudes towards mental health are changing in Pakistan, there is still a long road ahead to becoming a therapy-positive society. To dismiss the need for a therapist on campus today would mean consciously ignoring the impact of rapid changes in routine, fear of disease, and newer challenges to surmount as campuses open after more than half a year.

Stigma Around Therapy

In Pakistan, seeking help and going to therapy is not commonplace -in large part due to the cultural stigma associated with it. Visiting a mental health professional is often considered unnecessary, and anyone who sees a therapist may have to do so in confidence.

More importantly, the common perception that whoever sees a psychologist or psychiatrist must have some serious mental disorder keeps many ways from the doctor’s office. Therefore, if a student is facing problems related to their mental well-being, there is a good chance they may end up seeking the help they need.

However, if schools, colleges and universities were to hire mental health professionals and encourage students to go in for counselling sessions, it may well signal an important shift in the negative perceptions associated with therapy.

 Asking For Help

It would quite a reasonable expectation that students arriving back on campus this year would require more attention than before. Anxiety around the coronavirus protocols, social distancing, and the new normal is bound to affect young minds. Students returning to school have personal and psychological baggage stemming from the implications of the pandemic – these implications may stretch from the extensive isolation protocols all the way to the economic impact it has had on almost every family.

Prolonged duration spent in situations with dysfunctional family dynamics, depression, or just feeling lost, are just some of several factors that can come together to affect the personal and academic growth of students.

It is easy to overlook the mental well-being if you are a student dealing with coursework overload, adapting to the myriad of changes in your school environment, and the overall uncertainty looming over every facet of life including education. Students may not realize the need for counselling before it is too late, but schools know better. They can take proactive measures by hiring professionals and creating a safe space where the students can go to discuss mental health concerns plaguing them.

It is high time that we normalized the need for therapy, according to Naqsh-e-Fakhar, a thesis year architecture student from NCA. “It seems that we are learning to fight the war for survival at a much younger age now,” says Naqsh. “Everything has changed dramatically over the last few months. Our finances are all over the place, we are emotionally and physically drained, and to top it all off, there is so much work to get done before the thesis submission that we are all having mini-breakdowns every day.” According to the 20-something architecture student, “it would be a great relief to have a professional to talk to on campus because they could help us navigate through this feeling of emptiness, and underachievement.”

The Need of the Hour

Dr Tariq Aziz is a retired psychiatrist who now works from home and lends his expertise at a rehabilitation clinic for addicts believes, “It is crucial to have a psychologist on board in schools and universities, I cannot stress that enough.” The professional considers child psychology to be an oft-ignored matter in education and feels that children suffer most when their mental health issues are trivialized which is all too common in our society, unfortunately. “Every time a child underperforms, we start exerting more pressure on them to do well in class. Instead of treating the root cause of a student’s behavioral changes, we tend to worsen it by not seeking professional aid.”

According to Dr Aziz, “Children often mirror their family pathology.” When asked to elaborate he told Academia, “Children are often reacting to what is happening in-home or school environment by retaliating against the teacher, disrupting classes, or becoming aloof. ” The psychiatrist states, it is not always the child, but the family or the school bully who is the real problem. “We can only find out the deeper issue by probing into the matter, and if there is no one in school to counsel children in their time of need their mental health will suffer, and the real cause will go undetected.”

What To Do

The mental well-being of our students cannot be ignored, especially now. An on-campus mental health professional can determine through assessment the individual needs of a student dealing with something as common as exam stress to a more alarming eating disorder, depression, or a cognitive disorder.

“If our education system starts prioritizing mental health by recruiting professionals, then seeking help for mental health issues will not simply remain a thing you need, it will become a part of the education process, something you learn from that could help shape your future,” states Naqsh-e-fakhar thoughtfully.

To have a psychologist on campus can no longer be viewed as something that happens only in university campuses in the west. The Pakistani student is no different from their American or European counterparts. To think that Pakistani students are not facing body-image issues, fighting eating disorders, struggling with gender identity, are depressed, or are dealing with abuse would mean turning a blind eye towards a glaring problem.

It is time that we acknowledge that our students need all the help they can get, and for the concent of receiving therapy to becomes less of a controversial topic.

However, to encourage parents and children to seek professional aid, the aid must be made available first. To do so, policymakers and education stakeholders must come together and make it binding for the educational institutes to have a mental health professional on board.

It may be a long time before we achieve the above-stated goal but, in the meantime, we can at least initiate the conversation, pending for years.

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Nandrolone

Nandrolone Decanoate usi, interazioni, meccanismo d’azione Drugbank online

Nandrolone Decanoato

Nandrolone Decanoato è uno steroide anabolico indicato per la gestione dell’anemia dell’insufficienza renale aumentando l’emoglobina e la massa a cellule.

Nome generico Nandrolone Decanoato Drugbank Numero di adesione DB08804

Il nandrolone decanoato, noto anche come nandrolone caprinato, è uno steroide anabolico alchilato indicato nella gestione dell’anemia dell’insufficienza renale e come terapia aggiuntiva nel trattamento dell’osteoporosi senile e postmenopausa. 8,11,12,13 Il processo per la creazione di esteri di nandrolone è stato brevettato in Spagna nel 1959 15 e nel 1960, è stato descritto come una lunga durata di azione e un forte effetto anabolico rispetto al nandrolone e ad altri esteri. 11

Steroidi-veri – negozio di steroidi numero 1 in Italia

Nandrolone Decanoate è stata concessa l’approvazione della FDA il 5 ottobre 1962. 12

Tipo di piccole molecole di piccole molecole approvate, struttura illecita

Struttura per nandrolone decanoato (DB08804)

  • 19-Nortestosterone Decanoato
  • Nandrolone 17β-decanoato
  • Nandrolone Decanoato

Farmacologia

Il nandrolone decanoato è indicato nella gestione dell’anemia dell’insufficienza renale. 12 In Canada, è anche indicato come terapia aggiuntiva nel trattamento dell’osteoporosi senile e postmenopausa. 13

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Il nandrolone decanoato è uno steroide anabolico alchilato indicato nella gestione dell’anemia dell’insufficienza renale e come terapia aggiuntiva nel trattamento dell’osteoporosi senile e postmenopausa. 8,12,13 ha una lunga durata dell’azione in quanto viene data ogni 3-4 settimane e un’ampia finestra terapeutica come overdose acute sono rare. 8,13 pazienti devono essere consigliati in merito ai rischi di dare questo farmaco a pazienti con malattie cardiache, renali o epatiche. 13

Meccanismo di azione

Il nandrolone decanoato è idrolizzato a nandrolone, possibilmente da PDE7b. 3,5 nandrolone viene portato nelle cellule dall’endocitosi mediata dal recettore, dove interagisce con il recettore degli androgeni. 9,10 Dopo aver legame con il recettore degli androgeni, si verifica un cambiamento conformazionale, il recettore degli androgeni entra nel nucleo, si dimerizza e può quindi legarsi a segmenti di DNA per regolare la trascrizione. 10 androgeni possono anche regolare la trascrizione attraverso l’attivazione di ERK, AKT e MAPK; o legame con i fattori di trascrizione in modo competitivo e competitivo. 10

Una dose intramuscolare di 50 mg di nandrolone decanoato raggiunge una media cmax 2.14 ng/ml, con una media tmax di 30 ore e un AUC medio di 400 H*ng/ml. 1 a 100 mg dose intramuscolare di nandrolone decanoato raggiunge una media cmax 4.26 ng/ml, con una media tmax di 30 ore e un AUC medio di 862 H*ng/ml. 1 a 150 mg dose intramuscolare di nandrolone decanoato raggiunge una media cmax 5.16 ng/ml, con una media tmax di 72 ore e un AUC medio di 1261 H*ng/ml. 1

Volume di distribuzione

I dati relativi al legame percentuale proteico del decanoato di nandrolone non sono prontamente disponibili. Dopo che il nandrolone il decanoato viene idrolizzato in nandrolone, è legato all’ormone sessuale legante la globulina. 6

Il nandrolone decanoato è idrolizzato a nandrolone, possibilmente da PDE7b. 3,5 nandrolone è ulteriormente metabolizzato ai metaboliti urinari 19-norandrosterone, 19-noretiocholone e 19-norepiandosterone. 2,13 19-norandrosterone è 3-o-glucuronidato da UGT2B7, UGT 1A4, UGT2B4, UGT1A3 e UGT1A1. 4 19-norveetioicolanolone è 3-o-glucuronidato da UGT2B7, UGT2B4, UGT1A4, UGT1A10, UGT1A3 e UGT1A1. 4

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Il decanoato di nandrolone viene eliminato come metaboliti urinari, tuttavia i dati relativi all’eliminazione nelle feci non sono prontamente disponibili. 7 dati nei bovini mostrano che il nandrolone è eliminato al 30% nelle feci. 7

Il nandrolone decanoato ha una mezza vita di assorbimento di 6 giorni e una mezza vita di eliminazione di 4.3 ore. 13 studi alternativi hanno dimostrato che il nandrolone decanoato ha una mezza vita terminale di 7.1, 11.7 e 11.8 ore per dosi di 50, 100 e 150 mg rispettivamente. 1

50 mg, 100 mg e 150 mg di dosi di decanoato di nadrolone avevano calibri apparenti medi di 80.0 l/h, 74.3 l/h e 76.Rispettivamente 2 l/h. 1

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Migliorare il supporto alle decisioni e i risultati della ricerca con i nostri dati sugli effetti avversi strutturati.

I dati relativi al sovradosaggio acuto di nandrolone decanoato non sono prontamente disponibili. 13 Tuttavia, i pazienti che vivono un sovradosaggio cronico di steroidi anabolizzanti possono sperimentare effetti avversi tra cui la soppressione del testosterone e della spermatogenesi, la riduzione dei testicoli, la ridotta libido e la disfunzione erettile negli uomini; e soppresso estrogeni, progesterone e ovulazione, amenorrea e clitoromegalia nelle donne. 8 pazienti possono anche sperimentare effetti avversi neuropsichiatrici, cardiovascolari ed epatici. 8 steroidi anabolizzanti alchilati come il nandrolone decanoato hanno maggiori probabilità di causare effetti avversi epatici. 8 Trattare i pazienti con misure sintomatiche e di supporto.

L’intraperitoneal Ld50 nei topi è> 566 mg/kg. 14

Percorsi non disponibili Effetti farmacogenomici/ADRS

Interazioni

Queste informazioni non devono essere interpretate senza l’aiuto di un operatore sanitario. Se ritieni di aver sperimentato un’interazione, contatta immediatamente un operatore sanitario. L’assenza di un’interazione non significa necessariamente non esistono interazioni.